In the early 1900s, Korbinian Brodmann decided that the best way to tell apart the different parts of the brain would be by looking at cytoarchitecture or what types of cells and neurons are located there. By performing Nissl cell staining. Brodmann created maps of the cortex listing 52 different areas that have become a standard way of describing different brain regions. Although these areas have been updated a little bit over time, for the most part scientists have used these brain maps for over 100 years. So isn’t it time that we had an update?
Even the earliest neuroscientists wondered about which parts of the brain did what and how did they get their wrinkly shapes. From the perspective of evolution, having a wrinkly brain makes it easier for neurons to communicate to each other by bringing them together. But how do all those wrinkles form?